Specializing in amount and kind of protein consumed whereas taking semaglutide weight reduction drugs can protect lean mass and guarantee environment friendly metabolic functioning.
Weight reduction drugs with semaglutide because the lively ingredient create an vitality deficit as a result of medicine’s urge for food suppressing impact. This vitality deficit ensuing from urge for food suppression has been reported to be as a lot as a forty five % lower in day by day caloric consumption.1,2 A part of this deficit incudes misplaced energy derived from protein, which is vital for sustaining lean muscle mass. The lack of lean mass places sufferers in danger for bone mass loss, skeletal help, and diminished metabolic exercise.3 Inadequate protein chilly additionally exacerbate the GI uncomfortable side effects of semaglutide drugs (e.g., nausea). Additional, dropping lean mass makes our bodies run much less effectively relative to vitality expenditure. As a result of fats mass and lean mass are misplaced, it is very important optimize dietary intake to protect lean mass whereas dropping fats mass. This protein consumption optimization contains amount of protein and kind of protein.
Dietary Protein
Whereas there’s consensus surrounding the significance of protein for optimum well being, there stays some debate over the required quantity of day by day protein for optimum well being.4 The Really helpful Every day Allowance (RDA) for protein is 0.8 grams of protein for every kilogram of physique weight5, which is the minimal day by day protein consumption. Nevertheless, consuming plans that embody protein quantity above the RDA have reported higher advantages.4,5 For instance, a 2015 examine4 reported that consuming 1.2 – 1.6 g/kg physique weight yielded higher advantages for weight reduction within the contexts of type 2 diabetes or metabolic syndrome.
Analysis proof for inadequacy of the RDA for protein is mounting within the context of vitality restriction and weight reduction and the preservation of lean mass. For instance, in a examine with 130 members6, 66 have been randomly assigned to a PRO food plan which included 1.6 g/kg of day by day dietary protein (~30 % of vitality consumption) and 64 have been randomly assigned to a CHO which included 0.1 kg/g of dietary protein (~15 % of vitality consumption), outcomes confirmed that members within the PRO group misplaced extra weight and misplaced much less lean mas in comparison with the CHO group. When contemplating the optimum quantity of protein for sufferers on semaglutide drugs, elements comparable to weight, gender, age, and exercise degree should be thought of.7
Kinds of Protein
Shifting consuming plans to be extra protein-centric doesn’t essentially imply that sufferers must devour extra meat. Whereas animal merchandise comparable to lean beef, poultry, pork, or seafood are good sources of protein, plant-based choices comparable to complete grains, beans, legumes, greens, and nuts are additionally good sources of protein.7 Along with preserving lean mass, consuming high-quality protein all through the day can mitigate fatigue, a reported semaglutide aspect impact. The enzymes in protein will help semaglutide sufferers digest meals, thus mitigating GI uncomfortable side effects. Moreover, proteins oxygenate blood, pushing vitamins all through the physique.
Concerns for Sufferers taking Semaglutide
When prescribing semaglutide, it is very important contemplate the amount and forms of protein when working with sufferers to develop a healthy eating plan. The quantity of protein shall be decided by particular person elements comparable to age, gender, present weight, and exercise degree. The Dietary Tips for Adults7 is a helpful useful resource for wholesome consuming planning. Due to GI uncomfortable side effects related to semaglutide drugs, nutritionally designed meal replacements that embody whey protein and prebiotic fiber to assist help lean mass and handle GI signs needs to be thought of. Pairing weight reduction drugs with a wholesome consuming plan that’s supplemented with a nutritionally designed beverage will help mitigate dietary deficits and the widespread GI uncomfortable side effects related to semaglutide.
Sources:
3 Dietary protein and muscle mass: translating science to application and health benefit
5 Defining meal requirements for protein to optimize metabolic roles of amino acids
6 Dietary protein and muscle mass: Translating science to application and health benefit
