We’re thrilled to share findings that underscore the transformative potential of NOVOS Core in supporting wholesome ageing. This current research highlights NOVOS Core’s potential to increase lifespan by a formidable 18% in aged mice, equal to beginning remedy at 60 human years. The outcomes place NOVOS Core as a frontrunner in shopper anti-aging interventions, outperforming all dietary supplements and most of the most superior R&D longevity therapies.
Concerning the Research
The research was performed at Newcastle College’s Biosciences Institute by a group of esteemed researchers, together with Dr. Thomas von Zglinicki, Professor of Mobile Gerontology with over 43,000 citations, and Dr. Satomi Miwa, Lecturer on the Translational Biology of Ageing with over 10,000 citations. This analysis in contrast NOVOS Core towards each a senolytic drug mixture (a “optimistic management” of interventions beforehand proven to increase mouse lifespan) and a unfavourable management group with no intervention.
In complete, 38 male mice, aged 20 months originally of the research, have been divided into three teams: a unfavourable management group, a gaggle receiving NOVOS Core, and a senolytic group. Whereas NOVOS Core was administered each day, the senolytic remedy concerned two rounds of injections. Well being markers reminiscent of frailty and cognitive operate have been assessed each two months, including useful insights into NOVOS Core’s influence on general healthspan.
Key Findings from the Research
This research on NOVOS Core, our patent-pending longevity method, uncovered a number of notable outcomes, including important depth to the scientific understanding of its influence on ageing and healthspan. Right here’s a breakdown of the important thing findings that illustrate why this analysis is groundbreaking:
- 18% Lifespan Extension in Aged Mice
NOVOS Core prolonged lifespan by 18% in aged mice, equal to beginning remedy in human 60-year-olds. This spectacular relative improve surpasses the outcomes of any complement ever studied in aged mice, highlighting NOVOS Core’s effectiveness in selling longevity even when interventions start later in life. The longevity advantages exceed these of different well-known interventions, reminiscent of NR (nicotinamide riboside), glucosamine, and others. - A Highly effective, Accessible Different to Advanced Medical Interventions
The research underscores that NOVOS Core’s pure, multi-ingredient method can produce higher lifespan extension outcomes than invasive longevity therapies like TERT gene remedy, senolytic medicine like the mixture of dastatanib and quercetin, and hormone therapies like 17-alpha-estradiol. These findings counsel that efficient longevity interventions will be helpful even when began later in life. - Corresponding to R&D Senolytics however with Enhanced Security
Within the research, NOVOS Core matched the lifespan extension advantages of prescription-grade R&D senolytic injections of navitoclax mixed with BAM15, . Along with these longevity advantages, NOVOS Core delivers real-world health improvements that improve on a regular basis well-being. Not like many of those therapies, which will be invasive or carry potential unintended effects, NOVOS Core follows a gentler method by leveraging senostatic results—lowering the scale and slowing the formation of senescent cells somewhat than eliminating them outright. Analysis exhibits that not all senescent cells are harmful, and selectively preserving sure senescent cells can profit well being. This balanced method gives a safer, extra sustainable method to help longevity. - Focusing on All Twelve Mechanisms of Ageing
NOVOS Core’s unique formulation addresses all twelve scientifically recognized Mechanisms of Aging, a complete method that goes past the slender focus of many dietary supplements and therapies. This multi-target technique allows NOVOS Core to ship well being advantages throughout varied ageing pathways, setting it other than and outperforming single-ingredient therapies like NR, NMN, or much more superior approaches reminiscent of gene remedy. - Discount in Frailty and Cognitive Decline
Along with extending lifespan, NOVOS Core supplied constant, long-term enhancements in well being markers, together with reductions in frailty and preservation of cognitive operate. Whereas trending in the direction of statistical significance, the research authors prompt that beginning the intervention earlier could yield even stronger outcomes. - Enhanced Healthspan: Actual-World Advantages for On a regular basis Effectively-Being
Past longevity, the identical mechanisms contributing to lifespan extension additionally help high quality of life. These embrace enhancements in pores and skin well being, sleep high quality, power ranges, temper, and cognition—all areas wherein NOVOS Core customers have persistently reported optimistic modifications.
The Implications for Human Well being
Though this research was performed in mice, its findings maintain promising implications for human well being. NOVOS Core was developed utilizing human research and is particularly formulated to focus on the identical organic pathways that drive ageing in people. The lifespan extension noticed on this research is encouraging, however the rapid well being advantages that NOVOS Core customers report—reminiscent of enhanced power, temper, and cognitive operate—are already making a distinction in each day life.
In essence, NOVOS Core is not only about extending lifespan; it’s about enhancing healthspan—the standard of life within the years we stay. As analysis in longevity science progresses, we’re excited to see NOVOS Core set up itself as a number one, over-the-counter intervention within the anti-aging discipline.
At NOVOS, we’re proud to steer the patron longevity business with revolutionary options backed by rigorous science. By persevering with to put money into third-party analysis and our distinctive method to ageing, NOVOS Core stays some of the promising, protected, and accessible longevity options out there at the moment.
Learn the preprint of the research here.