To optimize the advantages of GLP-1 receptor agonists and mitigate the implications of semaglutide unwanted effects, it’s vital to pair these drugs with protein.
The lively ingredient in glucagon-like peptide 1 receptor agonists (GLP-1RA) similar to Ozempic and Wegovy is semaglutide. These drugs may help enhance blood sugar ranges for sufferers with kind 2 diabetes in addition to help weight reduction. Though GLP-1 receptor agonists are efficacious approaches to weight reduction, there are unwanted effects that warrant consideration and administration when prescribing these drugs to sufferers with weight problems. Essentially the most reported unwanted effects are GI associated, e.g., nausea, vomiting, diarrhea, and bloating, can compromise nutrition if not managed.1,2 Along with GI unwanted effects, unwanted effects of semaglutide embrace fatigue — and, there are additionally unwanted effects of stopping the medicine, similar to weight achieve. To optimize the advantages of GLP-1 receptor agonists and mitigate the implications of semaglutide unwanted effects, it’s vital to pair these drugs with protein.
The Significance of Protein When Taking GLP-1 Receptor Agonists
GLP-1 receptor agonists facilitate weight reduction as a result of they suppress one’s urge for food. Urge for food suppression coupled with GI unwanted effects places sufferers taking these drugs in danger for insufficient vitamin and falling wanting the really useful day by day allowances for his or her demographic group. As a result of these drugs result in fast weight reduction and a lower in caloric consumption to as a lot as a forty five p.c3,4, sufferers ought to make sure to eat lean protein. Protein is vital for preserving lean muscle mass, supporting a wholesome metabolism and organ well being.5,6
Protein’s advantages are optimized when it’s consumed all through the day. For instance, as reported in a latest examine7, an unbalanced distribution of protein consumption might cut back its efficacy for muscle preservation and well being. A 2015 examine discovered that at the least 1.2 – 1.6g/kg weight is really useful for preserving lean muscle mass.8
A facet impact of stopping GLP-1 receptor agonist drugs is weight achieve. Diets that embrace optimum protein consumption assist promote satiety. For instance, members following a excessive protein weight-reduction plan felt extra satiated all through the day in comparison with these within the excessive fats group.9 To cut back the danger of weight achieve when sufferers cease taking GLP-1 drugs, you will need to assist them build healthy eating habits whereas on these drugs.
Serving to Sufferers Mitigate Dietary Deficits and Semaglutide Aspect Results
GI unwanted effects and fatigue reported by sufferers taking GLP-1 drugs places them in danger for dietary deficits. Together with nutritionally designed shakes/drinks may help shore up dietary wants and assist sufferers meet their day by day really useful allowances for nutritional vitamins and minerals. Compliance with dietary adjustments is usually a vital issue when sufferers with weight problems are attempting to drop pounds, so together with nutritionally designed meal replacement products into their wholesome consuming plan warrants consideration. Meal replacements supply sufferers taking GLP-1 drugs a handy method to making sure they’re consuming a nutritionally balanced and nutritious diet. When GLP-1 drugs are prescribed for weight reduction, well being care professionals and dieticians ought to work with sufferers to design protein-forward eating plans that embrace distributing protein throughout meals to make sure greater than the minimal really useful day by day allowance is being met. Pairing weight reduction drugs with a wholesome consuming plan that’s supplemented with a nutritionally designed meal alternative can mitigate dietary deficits and GLP-1 GI unwanted effects.
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5 Defining meal requirements for protein to optimize metabolic roles of amino acids
7 Defining meal requirements for protein to optimize metabolic roles of amino acids
