RF Longevity Founder Gary Arendash talks immunity, cytokines and rising human longevity by means of bioengineering with FDA breakthrough tech.
Fourteen years in the past, scientists found exposing transgenic mice with Alzheimer’s to RF waves produced some thrilling outcomes; not solely have been the mice shielded from additional cognitive decline, however older mice even skilled a reversal of cognitive impairment [1]. It can come as no shock that the researchers set about leveraging this tech for a human strategy, creating a remedy referred to as Transcranial Radiofrequency Wave Therapy (TRFT). RF Longevity has realized this remedy in a tool referred to as MemorEM, a patented, noninvasive expertise that has acquired Breakthrough System designation from the US FDA as a possible remedy for Alzheimer’s in people.
Longevity.Know-how: The MemorEM machine delivers ultrahigh radio frequency electromagnetic waves to the mind by way of eight transmitters embedded in a cap and a management field worn on the arm. Customers put on the machine at residence for an hour a day, and expertise no sound or sensation related to the machine – they’ll just about get on with something throughout this time, though maybe not seize a bathe!
We sat down with Dr Gary Arendash, founding father of RF Longevity, to seek out out extra about MemorEM’s potential for Alzheimer’s remedy and lifespan extension and why all roads for a life extending intervention should undergo stopping or lessening dementia.
Gary Arendash on…
TRTF potential
Most significantly, the radio frequency rays that we’re utilizing are very protected. To my thoughts, TRFT is a entrance runner amongst gerotherapeutics to increase human lifespan, and that is for quite a lot of causes.
First, TRFT was the primary gerotherapeutic to be given breakthrough machine designation by FDA towards a serious illness of growing older. Second, TRFT stops and reverses a serious illness of growing older, particularly Alzheimer’s illness, albeit in small medical trials. Third, TREFT hasn’t proven any deleterious unwanted effects in medical trials – it’s really been given non -significant danger designation in america.
And really importantly, almost about longevity, in our Alzheimer’s topics, and I’m an Alzheimer’s researcher, TRFT, given over an prolonged two and a half yr time frame, resulted in no new illnesses of growing older – and these people averaged 70 years of age after they started the research. Lastly, in our 4 medical publications, we’ve recognized three main mechanisms of motion that we consider will collectively goal illnesses of growing older, quite a lot of them, and the growing older course of itself.
Mechanism of motion
Most neurodegenerative illnesses, comparable to Alzheimer’s and Parkinson’s, are attributable to mind toxins that self -aggregate. The 2 major toxins are β-amyloid (Aβ) and tau. Each of those molecules are made inside neurons, and of their singular kind, they’re innocuous. However as you age, they begin to self-aggregate. And so, you may get three, 4, 5, eight, 12 Aβ molecules collectively self-aggregating into oligomers; and the identical occurs for tau. Now, it’s these aggregated types of the neurotoxins that almost all of us in Alzheimer’s analysis now consider trigger the illness. I wish to point out strongly that it’s not the insoluble type of Aβ current in neuritic plaques and never the insoluble type of tau current in neurofibrillary tangles. Now, what does our expertise do? TRFT breaks up these toxins, these oligomeric toxins inside neurons and removes them from the mind. I don’t know of some other therapeutic that may do this.
Balancing immunity
Immune system dysfunction is the common signature widespread to most illnesses of growing older. Any critical longevity intervention area should handle this dysfunction, which is mainly an imbalanced immune system that happens throughout growing older. I’m enthusiastic about TRFT as a result of we’ve medical proof that TRFT can restore immune steadiness in each the human physique and the mind. And after I discuss imbalance and steadiness of the immune system, I’m referring to the effectors of the immune system – the cytokines. Professional-inflammatory cytokines and anti inflammatory cytokines are in steadiness once you’re in younger maturity and center age; nonetheless, as you enter older age in your 60s and 70s, the steadiness ideas in the direction of the pro-inflammatory element and that causes a continual state of irritation, which is the first explanation for main illnesses of growing older.
The vital factor to recollect right here is that centenarians, those that dwell above 100, by no means lose their balanced immune system. Going by means of their 60s, 70s, and 80s, each parts are strong and so they keep a low degree of irritation. They’ve an immune age 40 years youthful than their chronological age. That’s crucial, and to my information, TRFT is the one longevity intervention that may rejuvenate the human immune system. It does so by rebalancing cytokines. If the degrees are too low within the blood or the mind, these radio frequency rays convey it up. In the event that they’re too excessive, they’re introduced down.
TRFT makes crimson blood cell membranes extra fluid, permitting cytokines to go in or out extra simply. That’s precisely the attribute that centenarians have of their crimson blood cells – extra fluidity. The result’s a rebalancing of cytokines in blood and a dramatic discount in irritation. We see 50% discount in irritation within the physique with this expertise.
Subsequent steps
All roads for a life extending intervention undergo stopping or lessening dementia. Most distinguished is Alzheimer’s illness, however there are different varieties, vascular dementia and such. In case you’re lucky sufficient to dwell to be 85, one third of people that dwell to 85 have dementia. So that you’re going to need to take care of that for any form of longevity therapeutic. And we consider TRFT has the mechanism that may accomplish that. TRFT can be a mitochondrial enhancer to reinforce power manufacturing in neurons as we age, it balances immunity and reverses cognitive impairment.
The opposite factor that we see is that every one main Alzheimer’s markers in each blood and mind are beneficially affected by TRFT in sufferers in our research. No different Alzheimer’s therapeutic that I’m conscious of has proven this complete illness modifying impact. However, after all, a phrase of warning – these are small research. they’re not managed, so we positively want bigger managed research in Alzheimer’s sufferers earlier than FDA goes to approve this expertise.
Relating to longevity, taking a number of medicine to deal with a number of illnesses of growing older for a few years appears impractical. Quite, the enigma of extending human longevity is finest addressed by a single superior expertise that may safely goal many illnesses of growing older and the growing older course of itself – I consider TRFT is that superior expertise.
