Dominika Wilczok stories on this 12 months’s Summit, the place high specialists explored breakthroughs in ageing analysis and future healthspan improvements.
Days 3 and 4 of Longevity Summit Dublin had been a testomony to the convention’s dynamic and forward-thinking spirit. Full of insightful displays and strong discussions, today coated all types of longevity science and examined how it may be leveraged to meaningfully broaden each healthspan and lifespan. From the revealing of progressive AI platforms and breakthroughs in DNA restore to in-depth explorations of feminine reproductive longevity and governmental roles in healthspan funding, the summit showcased a wealthy tapestry of cutting-edge analysis and collaboration. Partaking keynotes, energetic panel discussions and vibrant networking occasions, together with a memorable Gala Dinner, ensured that the thrill and momentum by no means waned.
Here’s a taste of a few of the highlights and key takeaways from these two pivotal days, capturing the essence of an occasion that’s propelling the sector of longevity right into a promising future. Want you’d be there? Be sure you be a part of us in 2025!
DAY 3
Ben Goertzel began the day by presenting the Bioatomspace, the massive language mannequin fed with organic datasets, analysis papers and medical information, then skilled once more on logical expressions. Dr Alex Zhavoronkov, the CEO of Insilico Drugs, the world chief in AI drug discovery, defined the facility of multimodal, multiagent, multispecies platforms for advancing longevity analysis. Hanadie Yousef from Juvena Therapeutics offered the technique of leveraging proteins in cell secretomes for longevity. Its platform, JuveNET, goals to speed up drug discovery and growth. Ivan de Weber from Cortex Discovery went over their basis mannequin for drug property predictions and molecular docking.
The next module about DNA injury and restore was opened by Bjorn Schumacher, giving a keynote on pan-mammalian ageing clocks and stochastic variation. Joris Deelen defined the novel loci related to wholesome ageing and the progress within the research of the impact of uncommon protein-altering genetic variants in long-lived people. Morten Scheibye-Knudsen enriched the module by discussing sex- and tissue-specific ageing pathome and mapping mobile senescence.
Simisola Oke from GlycanAge, which was an occasion sponsor and likewise supplied on-site testing, satisfied the viewers that estrogen is a long life therapeutic.
After the lunch break, the dialogue moved to feminine reproductive longevity, the subject that’s lastly getting the eye it deserves. Niamh Joyce, Maria Marinova and Miguel Brieño-Enriquez shared their insights on how the analysis and interventions are advancing, together with NAD+ boosters, ovarian reserve influencing elements and demographic adjustments. The researchers concluded the module with an insightful panel with Tamara Radaković, Stasa Stankovic, and Jennifer Pearlman.
The concluding a part of the day was about governments’ involvement in longevity. We heard from William Greene from the Hevolution Basis, which lately mobilized a $400 million surge in healthspan funding. Michael Suk and Trey Goff continued the dialog by emphasizing the necessity for communication and cooperation.
Maria Blasco completed with the newest findings on one of many hallmarks of aging: telomere shortening. She reported her lab’s newest findings on the research of telomeres and telomerase and their position in human illness.
DAY 4
One would possibly assume that on the fourth day of a science convention, there could be some indicators of flagging or consideration wandering. It’s a testomony to the success of Longevity Summit Dublin that its thrilling speaker lineup efficiently prevented that from taking place. Rozalyn Anderson, Holly Brown-Borg, Matthew Scholz and Jana Buzkova explored the position of metabolism in ageing touching upon subjects such because the neurobiology of wholesome ageing, senolytics, NAD+ supplementation, protein restriction and development hormones.
The following module targeted on customized and focused therapies. Kotb Abdelmohsen, Lou Hawthorne and Brian Kennedy gave keynotes that confirmed the development of customized drugs general, whereas Alexandru-Ioan Voda confirmed how these interventions might be examined in a cat mannequin.
Persevering with the dialog from the day earlier than, Kamen Shoylev, Laurence Ion, Melissa King, Didier Coeurnelle and Jose Cordeiro targeted on the authorized and regulatory ecosystems that longevity entrepreneurship and scientists need to take care of in the event that they wish to do something aside from consuming others’ work. The sector that’s nonetheless very a lot in manufacturing is the analysis of novel species and strains in longevity. Georg Fuellen, Matae Ahn, Alec Lackmann, Emma Teeling and Kennedy Schaal mentioned this cutting-edge house.
The day concluded with a hearth chat between Alberto Aparicio and Aubrey de Gray.
However nonetheless a lot to report!
The convention additionally offered plenty of enjoyable, with a number of alternatives to community. A long life 5k enjoyable run raised members’ coronary heart charges, powering them with an endorphins enhance for the day. A number of snack and occasional breaks within the all-standing mode obtained individuals mingling and speaking, debating concepts and persevering with discussions in addition to increase an urge for food for the night social gatherings. At Saturday’s Gala Dinner, even essentially the most engrossing conversations had been placed on maintain when the drummer clad in Viking-like clothes took to the stage, beating out the rhythm for the waiters who turned out to be faucet dancers in disguise – we actually obtained to really feel some Irish spirit!
Two awards had been distributed. Alexander Fedintsev was named the “rising star” of longevity analysis. Aubrey de Gray admitted that Alexander had managed to vary Aubrey’s thoughts, one thing that was one of many many causes for the award. Dr Maria Blasco obtained the Excellent Contribution Award, a ravishing parchment portray impressed by an historic Irish artifact and created by the hand of Randy Hess, the artist on website.
Longevity Summit Dublin was definitely an occasion to recollect! More likely to be celebrated as a time when many tasks started, it, and different occasions prefer it, has the potential to remodeling the panorama of longevity science. This summit was greater than only a sequence of displays – it was a dynamic hub the place concepts had been exchanged, collaborations had been cast and the way forward for ageing analysis was charted. Attendees left impressed and energized, able to push the boundaries of what’s doable in longevity science. As we stay up for subsequent 12 months’s summit, the improvements and connections born from this gathering promise to considerably advance our understanding and enhancement of human lifespan and healthspan.
Read Dominika’s round-up of Days 1 and 2 HERE.
About Dominika Wilczok
With a background in utilizing AI for early Alzheimer’s detection, advocating in opposition to ageism, and establishing an NGO centered round Wholesome Longevity, for five years, Dominika has been working to shut the healthspan-lifespan hole. Her present work encompasses longevity drugs, and AI-driven approaches to finish ageing, and you’ll watch her TEDX speak on longevity drugs, ageing analysis and AI HERE.
